Junqi Niu Selected Research

GST-HG131

1/2022

Safety, Tolerability, and Pharmacokinetics of the Novel Hepatitis B Virus Expression Inhibitor GST-HG131 in Healthy Chinese Subjects: a First-in-Human Single- and Multiple-Dose Escalation Trial.

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Junqi Niu Research Topics

Disease

59	Infections 01/2022 - 01/2010
37	Chronic Hepatitis B 10/2022 - 01/2007
26	Fibrosis (Cirrhosis) 01/2022 - 11/2012
19	Chronic Hepatitis C 09/2021 - 01/2012
16	Hepatocellular Carcinoma (Hepatoma) 01/2022 - 02/2014
13	Liver Diseases (Liver Disease) 01/2022 - 02/2008
13	Hepatitis B 03/2020 - 09/2011
10	Liver Cirrhosis (Hepatic Cirrhosis) 10/2022 - 01/2014
10	Neoplasms (Cancer) 01/2022 - 11/2012
9	Inflammation (Inflammations) 09/2022 - 11/2012
8	Virus Diseases (Viral Diseases) 01/2022 - 01/2013
4	Hepatitis 09/2022 - 01/2014
3	Non-alcoholic Fatty Liver Disease 10/2022 - 12/2017
3	Anemia 03/2021 - 05/2019
3	Biliary Liver Cirrhosis (Primary Biliary Cirrhosis) 01/2021 - 05/2012
3	Disease Progression 01/2020 - 01/2019
3	Hepatitis C 11/2019 - 01/2018
2	Obesity 10/2022 - 01/2021
2	Liver Neoplasms (Liver Cancer) 01/2022 - 11/2019
2	End Stage Liver Disease 01/2022 - 01/2020
2	Ascites 10/2021 - 11/2020
2	Wounds and Injuries (Trauma) 10/2021 - 05/2021
2	Hepatolenticular Degeneration (Wilson's Disease) 01/2021 - 01/2016
2	Insulin Resistance 01/2020 - 06/2019
2	Persistent Infection 01/2020 - 11/2019
2	Chemical and Drug Induced Liver Injury 08/2019 - 05/2019
2	Chronic Hepatitis (Chronic Active Hepatitis) 08/2018 - 09/2016
2	Viremia 01/2018 - 02/2009
2	Type 2 Diabetes Mellitus (MODY) 01/2017 - 12/2015
2	Coinfection 09/2015 - 03/2014
1	Fatty Liver 10/2022
1	Gastrointestinal Hemorrhage (Hematochezia) 01/2022
1	Nausea 01/2022
1	Fever (Fevers) 01/2022
1	Dizziness (Lightheadedness) 01/2022
1	Acute-On-Chronic Liver Failure 01/2022
1	Brain Diseases (Brain Disorder) 01/2022
1	Respiratory Tract Infections (Respiratory Tract Infection) 01/2022
1	Communicable Diseases (Infectious Diseases) 12/2021
1	Hypoxia (Hypoxemia) 09/2021
1	Glioblastoma (Glioblastoma Multiforme) 09/2021

Drug/Important Bio-Agent (IBA)

29	Antiviral Agents (Antivirals)IBA 01/2022 - 02/2008
17	InterferonsIBA 01/2022 - 01/2014
16	Hepatitis B e AntigensIBA 10/2022 - 01/2007
12	Biomarkers (Surrogate Marker)IBA 10/2022 - 11/2012
12	Proteins (Proteins, Gene)FDA Link 09/2021 - 01/2012
12	Ribavirin (Virazole)FDA LinkGeneric 03/2021 - 01/2012
11	DNA (Deoxyribonucleic Acid)IBA 01/2022 - 01/2011
10	Hepatitis B Surface Antigens (HBsAg)FDA Link 09/2022 - 01/2012
9	Pharmaceutical PreparationsIBA 01/2022 - 01/2012
9	Aspartate Aminotransferases (Aspartate Transaminase)IBA 01/2021 - 03/2014
8	Alanine Transaminase (SGPT)IBA 09/2022 - 03/2014
8	RNA (Ribonucleic Acid)IBA 10/2021 - 09/2014
7	Transaminases (Aminotransferases)IBA 01/2022 - 12/2017
6	CytokinesIBA 03/2021 - 01/2011
6	Glucose (Dextrose)FDA LinkGeneric 01/2020 - 12/2011
6	Telbivudine FDA Link 01/2020 - 02/2008
5	BilirubinIBA 01/2022 - 01/2018
5	Lamivudine (Epivir)FDA Link 04/2015 - 01/2007
4	entecavir FDA Link 09/2022 - 06/2017
4	AlbuminsIBA 01/2022 - 01/2018
4	Therapeutic UsesIBA 01/2022 - 01/2011
4	Tenofovir (Viread)FDA Link 11/2021 - 01/2012
4	SofosbuvirIBA 09/2021 - 01/2018
3	Bile Acids and Salts (Bile Acids)IBA 01/2022 - 08/2019
3	VaccinesIBA 01/2022 - 01/2019
3	LipidsIBA 01/2021 - 12/2011
3	AntigensIBA 01/2020 - 01/2018
3	ApolipoproteinsIBA 09/2019 - 11/2016
3	InterleukinsIBA 11/2018 - 09/2011
3	Interleukin-10 (Interleukin 10)IBA 11/2018 - 05/2016
3	adefovir dipivoxil (Hepsera)FDA Link 02/2012 - 01/2010
2	pradefovirIBA 10/2022 - 01/2020
2	daclatasvirIBA 01/2022 - 11/2016
2	CollagenIBA 10/2021 - 05/2021
2	Toll-Like Receptors (Toll-Like Receptor)IBA 03/2021 - 11/2019
2	Biological ProductsIBA 01/2021 - 01/2018
2	Ethanol (Ethyl Alcohol)IBA 02/2020 - 01/2019
2	Insulin (Novolin)FDA Link 01/2020 - 06/2019
2	Hemoglobins (Hemoglobin)IBA 01/2020 - 08/2016
2	NucleotidesIBA 11/2019 - 01/2016
2	Indicators and Reagents (Reagents)IBA 04/2019 - 01/2014
2	alpha-Fetoproteins (alpha-Fetoprotein)IBA 04/2019 - 01/2015
2	AntibodiesIBA 01/2019 - 05/2012
2	Glycoproteins (Glycoprotein)IBA 01/2019 - 01/2014
2	pgRNAIBA 01/2019 - 01/2017
2	Lipoproteins (Lipoprotein)IBA 01/2019 - 11/2016
2	hydroxide ionIBA 02/2018 - 01/2012
2	Interferon-alpha (Interferon Alfa)IBA 11/2016 - 04/2016
2	Interleukin-33IBA 06/2012 - 01/2012
1	Mixed Function Oxygenases (Monooxygenases)IBA 01/2022
1	25-hydroxycholesterolIBA 01/2022
1	Deoxyribonucleases (DNase)FDA Link 01/2022
1	Carbon Tetrachloride (Tetrachloromethane)IBA 01/2022
1	GST-HG131IBA 01/2022
1	Fc gamma receptor IIBIBA 12/2021
1	Human Serum Albumin FDA LinkGeneric 10/2021
1	EchinomycinIBA 09/2021

Therapy/Procedure

28	Therapeutics 01/2022 - 02/2008
4	Liver Transplantation 01/2020 - 07/2013